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- $Unique_ID{BRK02415}
- $Pretitle{}
- $Title{Can You Be Altered Genetically After Birth?}
- $Subject{born inherited makeup genes genetic chromosomes viruses nuclei
- retroviruses vector altered special procedure procedures treatment treatments
- inherit inheritance gene chromosome virus viral alter chromosomal retrovirus
- birth}
- $Volume{P-27,R-27}
- $Log{}
-
- Copyright (c) 1992,1993 Tribune Media Services, Inc.
-
-
- Can You Be Altered Genetically After Birth?
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-
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-
- QUESTION: Can you help resolve a discussion between two friends? I am of the
- opinion that once you are born, your inherited makeup cannot be changed. My
- good friend says that there are new techniques that allow scientists to alter
- genes and change the makeup of a human being. It just doesn't seem possible,
- but we agreed to put the question to you. We hope you will answer it and
- settle our differences (on this question!).
-
- ------------------------------------------------------------------------------
-
- ANSWER: It isn't too many years ago that your position would have been
- considered totally correct and unchangeable. But the progress in genetic
- research has been truly incredible, and now there are techniques that permit
- scientists to change the genetic makeup of living individuals. And there is a
- great deal of discussion and controversy as to the ethics of such procedures.
- Genes are the complex chemicals in the chromosomes that carry the
- information that shapes the structures and functioning of all living material.
- In some cases the information is faulty, and transmits an "inherited" disease
- state. It would seem almost impossible to introduce the "correct" information
- into a living cell, if it weren't for the discovery of certain viruses that
- can enter human cells, and change the genetic information in the nuclei.
- Called "retroviruses," they provided a pathway or "vector" for changing the
- incorrect or faulty information.
- First, any harmful effects of the virus are removed by replacing its
- genes, transforming it into a harmless carrier. In research that is currently
- being carried on, white blood cells are removed from a patient, treated with
- retroviruses that contain the normal genetic information, and then
- reintroduced into the body. It is hoped that these cells will then repair the
- genetic defect.
- We are still a very long way from using this in every day medicine, but
- the fact is that we now have a method by which genes can be altered, and so I
- guess your friend wins this discussion.
-
- ----------------
-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
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-